What Are Designer Drugs?

The 7 Different Types of Designer Drugs

The U.S. Drug Enforcement Administration (DEA)⁴ recognizes 7 different kinds of designer drugs. They might add more in the future, but for now, these 7 are what they’ve been able to identify.

Synthetic Cannabinoids

Most synthetic cannabinoids began as an innocent research project⁵. Synthetic cannabinoids affect receptors throughout the body in the same way as THC (found in marijuana). It creates an elevated mood and sense of relaxation⁵. Almost all synthetic cannabinoids go by the street name Spice.

Compared to natural marijuana, Spice usually has a stronger effect⁵ and higher potential for toxicity. 

The chemical compound of Spice coats plant material, making it look like marijuana. You can smoke Spice like regular weed, snort it, or eat it. Its side effects include acute psychosis, anxiety, tachycardia, confusion, paranoia, and delusions. 

Phenethylamines

Phenethylamines are synthetic hallucinogens⁶, called 2Cs for their 2 connecting carbon molecules. Other street names include N-Bomb, based on the chemical name 25I-NBOMe. They communicate with serotonin receptors in the brain⁷. 

Phenethylamines recently hit the U.S. market after they were made to research serotonin receptors⁷. You can snort, smoke, inject, or swallow N-Bomb as a liquid or powder. After use, side effects like depersonalization, delirium, extreme confusion, violence, tachycardia, hyperreflexia, bizarre behavior, and heart failure can occur. 

Arylcyclohexylamines

Arylcyclohexylamines cause a dissociative high. The drug compounds of arylcyclohexylamines include ketamine, phencyclidines (PCP)⁸, and more. PCP goes by the street name “angel dust” as it’s typically “dusted” over marijuana and tobacco before smoking. Many synthetic arylcyclohexylamines were originally designed as anesthetics. PCP began that way too, before retiring to a veterinary anesthetic for its side effects. 

Ketamine isn’t as strong as PCP but still has addictive potential, especially at higher doses. Smaller doses, however, can be therapeutic. 

These designer drugs can cause violent behavior, hallucinations, amnesia, coma, ataxia, catatonia, and tachycardia. 

Tryptamines

Everyone has naturally occurring tryptamines—serotonin, melatonin, and others. But synthetic tryptamines act as hallucinogens⁹. They typically mimic the effects of LSD and DMT (psychedelic found in plants and animals). Street names include “Foxy”, “Foxy-Methoxy”, “Alpha-O”, and “5-MEO”. 

Tryptamines cause hallucinations and some stimulant effects⁹. They can also cause agitation, muscle tension, death, and rhabdomyolysis. Designer tryptamines come as pills, capsules, powders, or a liquid. 

Piperazines

Piperazines cause many of the same effects as ecstasy¹⁰, a stimulant. Similar to ecstasy, they’re marketed toward party-goers and even created to look like ecstasy. Its slang names include “party pills”, “Jax”, “Legal E”, “Flying Angel”, and “Pep X”.

Piperazines gained popularity worldwide as a mislabeled legal alternative to meth and MDMA (ecstasy)¹⁰. There’s little regulation or control over piperazines, making them an especially risky designer drug.

After taking piperazines, which come as a pill or powder, you might experience seizures, hallucinations, kidney failure, and respiratory acidosis.  

Pipradrol

Pipradrol, a stimulant¹¹, was first used as an antidepressant. It was also used to treat dementia and obesity. But pipradrol was quickly recalled due to its potential for abuse. Its effects mirror amphetamines—without some of the undesirable side effects. Pipradrols suppress appetite and don’t cause noticeable overexcitement, like other stimulants.

Pipradrol’s street names include MRD-108 and Alpha. Its toxic effects include hallucinations, death, anxiety, nausea, and convulsions. 

Cathinones

Cathinones mimic cocaine¹², ecstasy, and MDMA as designer central nervous system stimulant. They’re commonly called bath salts and cause a sense of euphoria. Being marketed as a designer drug, you can find bath salts online, in gas stations, smoke shops, and adult stores. 

Other street names include “Bliss,” “Blue Silk,” “Glass Cleaner,” and “Super Coke.” The active ingredient in cathinone comes from a khat plant. Scientists synthesized a drug based on the khat plant to form bath salts, which look like small, opaque rocks. Taking bath salts can cause psychosis, confusion, violence, hypertension, seizures, death, paranoia, and delusions. 

The makers of designer drugs suggest they’re a fun alternative to “real” drugs. Or, a way to take drugs without getting caught—or without accidentally hurting yourself. 

But neither proves true.

Are Designer Drugs Addictive?

Yes. Some designer drugs could be even more addictive than the drug they’re copying. Fentanyl, for example, mimics natural opioids like heroin¹³—but it’s 50 times more potent.  

Most designer drugs are supposed to be addictive¹. What begins as an experiment or coping tool can spiral out of control and into addiction. Because, with the easier accessibility of designer drugs, feeding the habit isn’t too difficult. Finding a reason to stop could feel unnecessary.

But you can. 

Getting Help for Designer Drug Use

 Designer drug addiction often responds well to the same treatments used for natural drug addictions. Some benzodiazepines can help¹ with long-term treatment and withdrawal. 

Some patients confront their need for treatment in an emergency room. An ER can get you stabilized and ready for the next steps in treatment, like a residential rehab with 24/7 support.

In treatment, you’ll likely have group and individual therapy to address the thoughts and behaviors behind your addiction. You might also join 12 Step meetings, which encourage you to find support in your higher power and in your peers. Many rehabs take insurance to make the cost of care more affordable. And your family can heal with you too, since most rehabs also offer family services. 
Treatment for designer drug use has the potential to unlock a life of recovery. To learn more about your recovery resources, you can browse our list of rehabs with reviews, pricing, insurance information, and photos.