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ONCE Center

ONCE Center

Mental Health
•
Outpatient
Private Pay

ONCE Center

Mental Health•Outpatient
About
Treatment
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ONCE offers a clinically guided psilocybin-assisted pathway for adults with concerns such as treatment-resistant depression, burnout, and trauma. Designed to fit around full lives, preparation and integration take place online, with just one day required in Amsterdam for the 1-on-1 psilocybin session. Their urban, retreat-like setting provides a private, comfortable space for the experience without requiring extended time away from work or family.

Prepare With Care and Intention

The process begins with a free conversation to explore what led the person to seek support and whether the psilocybin-assisted path might help. If they continue, a registered doctor reviews their medical history, well-being, and known risk factors before developing a personalised support plan. Online preparation sessions then lean into Internal Family Systems (IFS) therapy to explore the client’s intentions, personal history, and inner strengths, while preparing them for what non-ordinary states can feel like and how to navigate them.

Experience Psilocybin With Support

On the morning of the psilocybin session, the client meets 1-to-1 with their facilitator in a peaceful space with comfortable furniture, soft lighting, and blankets. After a brief orientation, the client can lie down, close their eyes, and listen to thoughtfully selected music as the experience unfolds. The facilitator remains nearby throughout, helping clients stay present with whatever arises without pressure to control the experience. Afterwards, the facilitator ensures the client feels grounded and stable before leaving.

Integrate Insights Into Daily Life

Lasting change depends on what happens after the psilocybin experience. During the period of increased neuroplasticity that follows, ONCE provides online integration sessions to help the client reflect on their experience and translate insights into specific actions. With their therapist, the client explores how these insights can shape relationships, work, decisions, and daily life, helping change become practical and sustainable.

AT A GLANCE

Center Overview

Location
Keizersgracht 312, 1016 EX Amsterdam, Netherlands View Map
Primary Focus
This center treats mental health conditions and co-occurring substance u...
Typical Program Length
30 days
Conditions We Treat
Anxiety, Burnout, Depression, Stress +1 More
Substance Use We Treat
Co-Occurring Disorders

+31 970 10223300

once.be
Payment

Pricing and Program Length

Psilocybin Session (Full Day)
€1590
Per Integration Session
€175
Per Preparation Session
€175
Medical Screening
€175
Psilocybin Session
$1,850
+31 970 10223300
Trust an Experienced, Research-Informed Team
Trust an Experienced, Research-Informed Team
ONCE brings scientific depth to an emerging field. Their clinical leadership combines psychiatry, neuroscience, and psychedelic research experience in Europe, informing a thoughtful approach to psilocybin-assisted therapy. Their model includes two dedicated therapists per client: one supporting online preparation and integration, and another guiding the in-person psilocybin session in Amsterdam.
Arrive With Every Detail Covered
Arrive With Every Detail Covered
ONCE helps make arriving in Amsterdam feel straightforward, with guidance on accommodation, the centre’s location, and what to expect upon arrival. They recommend arriving at least one day before the session and can assist with required travel documents. Clients choose where to stay, allowing time to settle in and approach the experience without rushing.
Reimagine Identity Beyond Work and Burnout
Reimagine Identity Beyond Work and Burnout
ONCE provides a pathway for clients whose daily lives continue to be affected by prolonged stress or exhaustion despite rest, time off, or previous support. Informed by emerging evidence, their burnout pathway helps clients reimagine their relationships with work and purpose. Afterwards, people report clearer priorities, stronger boundaries, and a renewed sense of possibility.
Draw Confidence From Emerging Evidence
Draw Confidence From Emerging Evidence
ONCE recognises psilocybin’s roots in longstanding spiritual and healing traditions, while grounding their approach in a growing body of modern clinical research. Institutions including Johns Hopkins, Imperial College London, and the University of Zurich have studied psilocybin-assisted approaches, with research showing promising results for conditions including depression.
Care Options

Levels of Care

Mental health care includes a range of services such as counseling, therapy, medication management, and support groups, all designed to address issues from everyday stress and anxiety to more severe conditions like depression and schizophrenia. These practices are essential for helping individuals manage their emotions, improve their relationships, and navigate life's challenges in healthier, more adaptive ways.
Not included
Residential
Not Offered at This Center
Intensive monitoring and care for conditions like depression, trauma, suicidality, and anxiety. Residential mental health facilities offer a safe setting with activities and structure, plus opportunities to practice life skills and bond with peers.
Included
Day Treatment
In a PHP, patients live at home but follow an intensive schedule of treatment. Most programs require you to be on-site for about 40 hours per week.
Included
Outpatient
Outpatient treatment offers flexible therapeutic and medical care without the need to stay overnight in a hospital or inpatient facility. Outpatient care typically offers a range of therapies and medical interventions individuals can attend alongside daily life.
Included
Virtual & In-Home Care
The delivery of therapeutic services utilizing technology such as video conferencing, online messaging or phone calls, allowing for flexibility, comfort and increased access to care.
Included
Licensed Primary Mental Health
Licensed primary mental health facilities provide specialized care for diagnosing and treating mental health conditions. By offering early intervention and comprehensive services, they promote overall well-being and prevent long-term complications.
Included
Co-Occurring Substance Use
Substance use disorders often occur alongside primary mental health conditions. Programs for co-occurring substance use disorders focus on both conditions, tailoring treatment for comprehensive recovery.
Treatment

Your Care Options

Specializations

Internal Family Systems Therapy
Mindfulness Therapy
Anxiety
Burnout
Depression
Stress
Trauma

Who We Treat

Men
Women
Couples
Older Adults
Executives
Men and Women
Veterans

Approaches

Medical
Personalized Treatment

Therapies

1-on-1 Counseling
Internal Family Systems Therapy
Mindfulness Therapy

Languages

Dutch
English
Russian
Ukrainian

Conditions We Treat

Anxiety
Burnout
Depression
Stress
Trauma

Substances We Treat

Co-Occurring Disorders

We love hearing about your treatment experience

+31 970 10223300

Frequently Asked Questions

Further Research

While costs may vary due to program length and insurance benefits, it typically costs €1590.
The following therapies are included: 1-on-1 counseling, internal family systems therapy and more.
Amsterdam, Netherlands, Europe.
The typical length is 30 days.
ONCE Center provides day treatment, licensed primary mental health and more.

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