


Dr. Lauren Geoffrion graduated medical school from Loma Linda University in May 2021. Throughout medical school, she worked on several publications in collaboration with physicians at Loma Linda. She researched and wrote for several psychiatry publications as well as writing an abstract for her research featured in the Journal of Investigative Medicine in 2018.

Kristen Fuller, M.D., enjoys writing about evidence-based topics in the cutting-edge world of mental health and addiction medicine and contributes to medicine board education.




Dr. Lauren Geoffrion graduated medical school from Loma Linda University in May 2021. Throughout medical school, she worked on several publications in collaboration with physicians at Loma Linda. She researched and wrote for several psychiatry publications as well as writing an abstract for her research featured in the Journal of Investigative Medicine in 2018.

Kristen Fuller, M.D., enjoys writing about evidence-based topics in the cutting-edge world of mental health and addiction medicine and contributes to medicine board education.
Mental health disorders like bipolar disorder commonly occur alongside substance use disorders (SUDs), the diagnostic term for addiction, because they tend to have the same risk factors, and each disorder can worsen the other.1 When a person has both a mental illness and a substance use disorder, it is known as co-occurring disorders, or comorbidity.1 While co-occurring addiction and bipolar disorder can be challenging, evidence-based treatment can lead to positive health outcomes.
Bipolar disorder is a mood disorder in which a person’s mood can greatly fluctuate between depressive and manic episodes.2Depressive episodes are often characterized by excessive sadness and loss of interest in favored activities.2 Manic episodes are often characterized by intense euphoria, energy, and activity.2 Bipolar disorder can present as episodic, occurring at varying intervals, or chronic, reoccurring constantly.3
Bipolar disorder is classified by the Diagnostic and statistical manual of mental disorders, 5th Edition (DSM-5), in a category known as “Bipolar and Related Disorders.”4, 5 The two commonly known disorders in this category are bipolar I and bipolar II.5, 6
Bipolar I is defined as having at least one diagnosable manic episode with or without depressive episodes.5, 6 Bipolar II is defined as having at least one hypomanic and one depressive episode.5, 6 Hypomanic episodes include many of the same symptoms as manic episodes but are not severe enough to impair a person socially or at work.2
It’s estimated that around 20% of people with bipolar disorder attempt suicide at some time in their lives.2 Some mental health professionals believe it to be the mental disorder with the highest suicide risk.2
There is no single cause for bipolar disorder.3 Like other mental health disorders, bipolar disorder is thought to be caused by a combination of genetics, brain structure, and environment.3 Evidence suggests that bipolar disorder occurs equally in men and women.5
Several factors may contribute to the risk of developing bipolar disorder, yet a person can have known risk factors and never develop bipolar disorder. Risk factors for bipolar disorder can include:3, 5, 6
If you think you or a loved one has bipolar disorder, a mental healthcare professional can provide a thorough assessment and give a diagnosis, if applicable. Since bipolar and related disorders have different diagnostic criteria, it’s important to see a professional to receive a diagnosis.
The diagnostic criteria for bipolar I are broken down into manic, hypomanic episodes, and major depressive episodes in the DSM-5.6
A depressive episode is recognized by symptoms of:2
A manic episode is characterized by symptoms such as:2
The criteria for diagnosing bipolar and related disorders must be carefully evaluated to make sure symptoms aren’t being caused by another mental health disorder.2, 3, 6 The causes can be difficult to diagnose because many other mental health and personality disorders share the same traits.3
Approximately 65% of people with bipolar will develop a substance use disorder at some time in their life.2 About 30% of people with bipolar disorder in clinical settings also misuse alcohol.2
Individuals with co-occurring disorders tend to have lower treatment adherence for SUDs, longer mood episodes, worse recovery of functional skills, and more hospitalizations.2 Sometimes only one of the two or more disorders are treated, or the behaviors motivated by each disorder tend to worsen the other behavior.1 If they are not treated together, it can be extremely difficult to overcome the disorders one at a time.1
The combination of bipolar disorder and addiction can occasionally worsen a person’s symptoms during manic or depressive episodes.4 It is not known exactly why bipolar disorder and SUDs commonly co-occur; however, the explanation that alcohol or drugs may be a form of ‘self-medication’ in which people relieve their psychological suffering appears true for many.4
Additionally, it is thought that both bipolar disorder and addiction come from the same genetic anomalies, and thus people with one are at risk for the other.4
The co-occurrence of bipolar and SUDs can complicate treatment; however, they should be treated together to achieve more positive health outcomes. 2, 4 It’s possible that cognitive behavioral therapy, integrated therapy, and relapse prevention techniques may be helpful in:2
Research on medications that treat both bipolar and SUDs is limited. However, there are several medications that may help treat the symptoms of bipolar disorder, including:4
Depending on a person’s needs, these and other methods can be used to create an individualized treatment plan with the support of your treatment team.
If you or a loved one is ready to seek rehab for a substance use disorder, explore your options and reach out to a rehab center using our rehab directory tool today!
National Institute on Drug Abuse. (2018, August 1). Comorbidity: Substance use disorders and other mental illnesses drugfacts. https://nida.nih.gov/publications/drugfacts/comorbidity-substance-use-disorders-other-mental-illnesses
Substance Abuse and Mental Health Services Administration. (2020). Substance use disorder treatment for people with co-occurring disorders. Treatment improvement protocol (TIP) series, No.42. https://store.samhsa.gov/sites/default/files/SAMHSA_Digital_Download/PEP20-02-01-004_Final_508.pdf
National Institute of Mental Health. (2022). Bipolar disorder. https://www.nimh.nih.gov/health/publications/bipolar-disorder
Substance Abuse and Mental Health Services Administration. (2016). An introduction to bipolar disorder and co-occurring substance use disorders. Advisory. 15(2). https://store.samhsa.gov/sites/default/files/d7/priv/sma16-4960.pdf
Rowland, T.A., & Marwaha, S. (2018, September). Epidemiology and risk factors for bipolar disorder. Therapeutic Advances in Psychopharmacology. 8(9), 251-269. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116765/
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